Sunday, 2 December 2012


Nanobiotechnology: Versatile 3-D Nanostructures Using DNA 'Bricks'

ScienceDaily (Nov. 29, 2012) — Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created more than 100 three-dimensional (3D) nanostructures using DNA building blocks that function like Lego® bricks -- a major advance from the two-dimensional (2D) structures the same team built a few months ago.
Computer-generated 3D models (left) and corresponding 2D projection microscopy images (right) of nanostructures self-assembled from synthetic DNA strands called DNA bricks. A master DNA brick collection defines a 25-nanometer cubic "molecular canvas" with 1000 voxels. By selecting subsets of bricks from this canvas, Ke et al. constructed a panel of 102 distinct shapes exhibiting sophisticated surface features as well as intricate interior cavities and tunnels. These nanostructures may enable diverse applications ranging from medicine to nanobiotechnology and electronics. (Credit: Yonggang Ke, Wyss Institute, Harvard University)
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